Drug interactions
Azathioprine + Tongkat ali
Severity: Minor
Azathioprine and Tongkat ali: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tongkat ali has been described as having immunomodulating activity, but evidence of a clinically meaningful additive immunosuppressive effect with azathioprine is weak. The interaction is mostly theoretical.
What this interaction means in plain words
Azathioprine and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible immunomodulatory effects of herbal constituents; the mechanism is not well established.
What to do
Advise patients to disclose herbal product use and avoid unnecessary supplements. Monitor for infection and graft or disease control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine Contraindicated
- Azathioprine + Bcg vaccine live Contraindicated
- Azathioprine + Febuxostat Contraindicated
- Azathioprine + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine live Contraindicated
Frequently asked questions
Can I take Azathioprine with Tongkat ali?
MediHelp rates the interaction as minor. Azathioprine and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tongkat ali has been described as having immunomodulating activity, but evidence of a clinically meaningful additive immunosuppressive effect with azathioprine is weak. The interaction is mostly theoretical.
How serious is the interaction between Azathioprine and Tongkat ali?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to disclose herbal product use and avoid unnecessary supplements. Monitor for infection and graft or disease control.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
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