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Drug interactions

Azathioprine + Travelers diarrhea and cholera vaccine inactivated

Severity: Minor

Azathioprine and Travelers diarrhea and cholera vaccine inactivated: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Azathioprine may weaken the immune response to this inactivated oral vaccine, resulting in less protection against cholera and ETEC diarrhea.

What this interaction means in plain words

Azathioprine and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Azathioprine impairs lymphocyte proliferation and humoral responses to vaccination.

What to do

Vaccinate before travel if possible and reinforce food and water hygiene. No dose change is needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Azathioprine with Travelers diarrhea and cholera vaccine inactivated?

MediHelp rates the interaction as minor. Azathioprine and Travelers diarrhea and cholera vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Azathioprine may weaken the immune response to this inactivated oral vaccine, resulting in less protection against cholera and ETEC diarrhea.

How serious is the interaction between Azathioprine and Travelers diarrhea and cholera vaccine inactivated?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before travel if possible and reinforce food and water hygiene. No dose change is needed.

What other medicines interact with Azathioprine?

MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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