Drug interactions
Azelastine-fluticasone + Carisoprodol
Severity: Moderate
Azelastine-fluticasone and Carisoprodol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carisoprodol is a centrally acting sedating muscle relaxant. Adding azelastine may increase drowsiness, dizziness and psychomotor impairment.
What this interaction means in plain words
Azelastine-fluticasone and Carisoprodol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azelastine-fluticasone belongs to Respiratory; Carisoprodol belongs to Musculoskeletal.
Why it happens
Additive central nervous system depression.
What to do
Monitor for excessive sedation and advise caution with driving. Reduce doses or stop azelastine if impairment develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azelastine-fluticasone
- Azelastine-fluticasone + Calcium / magnesium / potassium / sodium oxybates Major
- Azelastine-fluticasone + Sodium oxybate Major
- Alfentanil + Azelastine-fluticasone Moderate
- Alprazolam + Azelastine-fluticasone Moderate
- Amitriptyline + Azelastine-fluticasone Moderate
- Amobarbital + Azelastine-fluticasone Moderate
Other interactions of Carisoprodol
Frequently asked questions
Can I take Azelastine-fluticasone with Carisoprodol?
MediHelp rates the interaction as moderate. Azelastine-fluticasone and Carisoprodol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carisoprodol is a centrally acting sedating muscle relaxant. Adding azelastine may increase drowsiness, dizziness and psychomotor impairment.
How serious is the interaction between Azelastine-fluticasone and Carisoprodol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and advise caution with driving. Reduce doses or stop azelastine if impairment develops.
What other medicines interact with Azelastine-fluticasone?
MediHelp also lists interactions of Azelastine-fluticasone with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Azelastine-fluticasone page.
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