Drug interactions
Azelastine-fluticasone + Scullcap
Severity: Minor
Azelastine-fluticasone and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Scullcap is a herbal product traditionally used as a sedative and may add to azelastine drowsiness. Evidence is limited and the interaction is largely theoretical.
What this interaction means in plain words
Azelastine-fluticasone and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; not well characterized.
What to do
Advise the patient to monitor for excess drowsiness and avoid driving if affected. Discontinue the herb if sedation is problematic.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azelastine-fluticasone
- Azelastine-fluticasone + Calcium / magnesium / potassium / sodium oxybates Major
- Azelastine-fluticasone + Sodium oxybate Major
- Alfentanil + Azelastine-fluticasone Moderate
- Alprazolam + Azelastine-fluticasone Moderate
- Amitriptyline + Azelastine-fluticasone Moderate
- Amobarbital + Azelastine-fluticasone Moderate
Frequently asked questions
Can I take Azelastine-fluticasone with Scullcap?
MediHelp rates the interaction as minor. Azelastine-fluticasone and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Scullcap is a herbal product traditionally used as a sedative and may add to azelastine drowsiness. Evidence is limited and the interaction is largely theoretical.
How serious is the interaction between Azelastine-fluticasone and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise the patient to monitor for excess drowsiness and avoid driving if affected. Discontinue the herb if sedation is problematic.
What other medicines interact with Azelastine-fluticasone?
MediHelp also lists interactions of Azelastine-fluticasone with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Azelastine-fluticasone page.
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