Drug interactions
Azelastine-fluticasone + Triazolam
Severity: Moderate
Azelastine-fluticasone and Triazolam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triazolam is a short-acting benzodiazepine hypnotic, and azelastine can add to sedation. The combination may worsen drowsiness, dizziness and psychomotor impairment.
What this interaction means in plain words
Azelastine-fluticasone and Triazolam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression.
What to do
Use the lowest effective triazolam dose and monitor for excess sedation. Advise against driving and alcohol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azelastine-fluticasone
- Azelastine-fluticasone + Calcium / magnesium / potassium / sodium oxybates Major
- Azelastine-fluticasone + Sodium oxybate Major
- Alfentanil + Azelastine-fluticasone Moderate
- Alprazolam + Azelastine-fluticasone Moderate
- Amitriptyline + Azelastine-fluticasone Moderate
- Amobarbital + Azelastine-fluticasone Moderate
Frequently asked questions
Can I take Azelastine-fluticasone with Triazolam?
MediHelp rates the interaction as moderate. Azelastine-fluticasone and Triazolam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triazolam is a short-acting benzodiazepine hypnotic, and azelastine can add to sedation. The combination may worsen drowsiness, dizziness and psychomotor impairment.
How serious is the interaction between Azelastine-fluticasone and Triazolam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective triazolam dose and monitor for excess sedation. Advise against driving and alcohol.
What other medicines interact with Azelastine-fluticasone?
MediHelp also lists interactions of Azelastine-fluticasone with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Azelastine-fluticasone page.
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