Drug interactions
Azficel-t + Celecoxib
Severity: Moderate
Azficel-t and Celecoxib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is administered by intradermal injection after a skin biopsy, and NSAID use can increase bruising and bleeding at these sites. Product labeling advises against concurrent NSAID use around the procedures.
What this interaction means in plain words
Azficel-t and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
NSAID-mediated platelet inhibition increases bleeding and bruising at biopsy and injection sites.
What to do
Hold celecoxib for the period recommended in labeling around biopsy and injection visits, using acetaminophen if analgesia is needed. Inspect procedure sites for excess bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Azficel-t with Celecoxib?
MediHelp rates the interaction as moderate. Azficel-t and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is administered by intradermal injection after a skin biopsy, and NSAID use can increase bruising and bleeding at these sites. Product labeling advises against concurrent NSAID use around the procedures.
How serious is the interaction between Azficel-t and Celecoxib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Hold celecoxib for the period recommended in labeling around biopsy and injection visits, using acetaminophen if analgesia is needed. Inspect procedure sites for excess bleeding.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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