Drug interactions
Azficel-t + Diclofenac
Severity: Moderate
Azficel-t and Diclofenac: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs may increase bruising and bleeding at the biopsy and injection sites used for azficel-T treatment. The product labeling advises against concomitant NSAID use around these procedures.
What this interaction means in plain words
Azficel-t and Diclofenac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
NSAID inhibition of platelet cyclooxygenase impairs platelet aggregation and prolongs bleeding.
What to do
Hold diclofenac for the period around biopsy and injections as advised in the labeling, and use paracetamol for analgesia if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Frequently asked questions
Can I take Azficel-t with Diclofenac?
MediHelp rates the interaction as moderate. Azficel-t and Diclofenac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs may increase bruising and bleeding at the biopsy and injection sites used for azficel-T treatment. The product labeling advises against concomitant NSAID use around these procedures.
How serious is the interaction between Azficel-t and Diclofenac?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Hold diclofenac for the period around biopsy and injections as advised in the labeling, and use paracetamol for analgesia if needed.
What other medicines interact with Diclofenac?
MediHelp also lists interactions of Diclofenac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Diclofenac page.
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