Drug interactions
Azficel-t + Ketoprofen
Severity: Moderate
Azficel-t and Ketoprofen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs impair platelet function and may increase bruising or bleeding at the biopsy and injection sites used for azficel-T treatment. The product labeling advises against concomitant NSAID use around these procedures.
What this interaction means in plain words
Azficel-t and Ketoprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Reversible platelet COX-1 inhibition by ketoprofen increases procedural bleeding tendency.
What to do
Hold ketoprofen for an appropriate period around the biopsy and injections, as directed by the product labeling, and use an alternative analgesic such as paracetamol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Frequently asked questions
Can I take Azficel-t with Ketoprofen?
MediHelp rates the interaction as moderate. Azficel-t and Ketoprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs impair platelet function and may increase bruising or bleeding at the biopsy and injection sites used for azficel-T treatment. The product labeling advises against concomitant NSAID use around these procedures.
How serious is the interaction between Azficel-t and Ketoprofen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Hold ketoprofen for an appropriate period around the biopsy and injections, as directed by the product labeling, and use an alternative analgesic such as paracetamol.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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