Drug interactions
Azficel-t + Sulindac
Severity: Moderate
Azficel-t and Sulindac: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is injected intradermally after skin biopsy, and NSAIDs can increase bruising and bleeding at the biopsy and injection sites. Labeling advises against concurrent NSAID use around these procedures.
What this interaction means in plain words
Azficel-t and Sulindac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
NSAID-induced inhibition of platelet aggregation increases bleeding and bruising at procedure sites.
What to do
Hold sulindac before and around biopsy and injection sessions as directed by the prescriber, using an alternative analgesic if needed. Monitor the sites for bleeding or hematoma.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Frequently asked questions
Can I take Azficel-t with Sulindac?
MediHelp rates the interaction as moderate. Azficel-t and Sulindac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is injected intradermally after skin biopsy, and NSAIDs can increase bruising and bleeding at the biopsy and injection sites. Labeling advises against concurrent NSAID use around these procedures.
How serious is the interaction between Azficel-t and Sulindac?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Hold sulindac before and around biopsy and injection sessions as directed by the prescriber, using an alternative analgesic if needed. Monitor the sites for bleeding or hematoma.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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