Drug interactions
Azilsartan + Choline magnesium trisalicylate
Severity: Minor
Azilsartan and Choline magnesium trisalicylate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Choline magnesium trisalicylate has less prostaglandin inhibition than typical NSAIDs, but at high doses it may still reduce azilsartan's antihypertensive effect and affect renal function in vulnerable patients.
What this interaction means in plain words
Azilsartan and Choline magnesium trisalicylate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak inhibition of renal prostaglandin synthesis can reduce renal perfusion and oppose ARB effect.
What to do
Monitor blood pressure and renal function if used regularly at high doses, especially in older or dehydrated patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan
- Aliskiren + Azilsartan Contraindicated
- Azilsartan + Sparsentan Contraindicated
- Amifostine + Azilsartan Major
- Amlodipine-benazepril + Azilsartan Major
- Amlodipine-perindopril + Azilsartan Major
- Azilsartan + Benazepril Major
Frequently asked questions
Can I take Azilsartan with Choline magnesium trisalicylate?
MediHelp rates the interaction as minor. Azilsartan and Choline magnesium trisalicylate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Choline magnesium trisalicylate has less prostaglandin inhibition than typical NSAIDs, but at high doses it may still reduce azilsartan's antihypertensive effect and affect renal function in vulnerable patients.
How serious is the interaction between Azilsartan and Choline magnesium trisalicylate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and renal function if used regularly at high doses, especially in older or dehydrated patients.
What other medicines interact with Azilsartan?
MediHelp also lists interactions of Azilsartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Azilsartan page.
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