Drug interactions
Azilsartan + Insulin aspart protamine / insulin aspart
Severity: Minor
Azilsartan and Insulin aspart protamine / insulin aspart: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ARBs may slightly enhance insulin sensitivity and in some patients increase the risk of hypoglycemia with insulin. The effect is usually small but can be noticed when starting the ARB.
What this interaction means in plain words
Azilsartan and Insulin aspart protamine / insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible improvement in insulin sensitivity from angiotensin receptor blockade, adding to insulin glucose-lowering.
What to do
Monitor blood glucose more often when starting azilsartan and reduce insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan
- Aliskiren + Azilsartan Contraindicated
- Azilsartan + Sparsentan Contraindicated
- Amifostine + Azilsartan Major
- Amlodipine-benazepril + Azilsartan Major
- Amlodipine-perindopril + Azilsartan Major
- Azilsartan + Benazepril Major
Frequently asked questions
Can I take Azilsartan with Insulin aspart protamine / insulin aspart?
MediHelp rates the interaction as minor. Azilsartan and Insulin aspart protamine / insulin aspart have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ARBs may slightly enhance insulin sensitivity and in some patients increase the risk of hypoglycemia with insulin. The effect is usually small but can be noticed when starting the ARB.
How serious is the interaction between Azilsartan and Insulin aspart protamine / insulin aspart?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more often when starting azilsartan and reduce insulin dose if hypoglycemia occurs.
What other medicines interact with Azilsartan?
MediHelp also lists interactions of Azilsartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Azilsartan page.
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