Drug interactions
Azilsartan + Insulin inhaled
Severity: Moderate
Azilsartan and Insulin inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity, so patients on insulin can have lower glucose levels and a higher risk of hypoglycemia after an ARB is started. The effect is usually modest but can matter in patients with tight glycemic control or variable intake.
What this interaction means in plain words
Azilsartan and Insulin inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Probable pharmacodynamic additive glucose lowering through improved insulin sensitivity with ARBs; the exact mechanism is not fully established.
What to do
Monitor blood glucose more frequently when azilsartan is started or stopped, and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azilsartan
- Aliskiren + Azilsartan Contraindicated
- Azilsartan + Sparsentan Contraindicated
- Amifostine + Azilsartan Major
- Amlodipine-benazepril + Azilsartan Major
- Amlodipine-perindopril + Azilsartan Major
- Azilsartan + Benazepril Major
Frequently asked questions
Can I take Azilsartan with Insulin inhaled?
MediHelp rates the interaction as moderate. Azilsartan and Insulin inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Angiotensin receptor blockers may improve insulin sensitivity, so patients on insulin can have lower glucose levels and a higher risk of hypoglycemia after an ARB is started. The effect is usually modest but can matter in patients with tight glycemic control or variable intake.
How serious is the interaction between Azilsartan and Insulin inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when azilsartan is started or stopped, and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Azilsartan?
MediHelp also lists interactions of Azilsartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Azilsartan page.
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