Drug interactions
Azilsartan + Insulin lispro
Severity: Minor
Azilsartan and Insulin lispro: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and can modestly strengthen the glucose-lowering effect of insulin. Hypoglycemia may occur, mainly when treatment is started or the ARB dose is raised.
What this interaction means in plain words
Azilsartan and Insulin lispro have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan belongs to Cardiovascular; Insulin lispro belongs to Endocrine.
Why it happens
ARBs may enhance insulin sensitivity, producing an additive pharmacodynamic glucose-lowering effect.
What to do
Monitor blood glucose more often when azilsartan is started or titrated. Reduce the mealtime insulin dose if hypoglycemia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan
- Aliskiren + Azilsartan Contraindicated
- Azilsartan + Sparsentan Contraindicated
- Amifostine + Azilsartan Major
- Amlodipine-benazepril + Azilsartan Major
- Amlodipine-perindopril + Azilsartan Major
- Azilsartan + Benazepril Major
Other interactions of Insulin lispro
Frequently asked questions
Can I take Azilsartan with Insulin lispro?
MediHelp rates the interaction as minor. Azilsartan and Insulin lispro have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and can modestly strengthen the glucose-lowering effect of insulin. Hypoglycemia may occur, mainly when treatment is started or the ARB dose is raised.
How serious is the interaction between Azilsartan and Insulin lispro?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more often when azilsartan is started or titrated. Reduce the mealtime insulin dose if hypoglycemia develops.
What other medicines interact with Azilsartan?
MediHelp also lists interactions of Azilsartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Azilsartan page.
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