Drug interactions
Azilsartan + Insulin neutral human-insulin isophane protamine human
Severity: Minor
Azilsartan and Insulin neutral human-insulin isophane protamine human: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and can enhance the glucose-lowering effect of insulin, occasionally causing hypoglycemia. The effect is generally modest and most apparent after starting the ARB.
What this interaction means in plain words
Azilsartan and Insulin neutral human-insulin isophane protamine human have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan belongs to Cardiovascular; Insulin neutral human-insulin isophane protamine human belongs to Endocrine.
Why it happens
Likely improved insulin sensitivity from angiotensin II receptor blockade; the mechanism is not fully established.
What to do
Monitor blood glucose more frequently after starting or changing azilsartan and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin neutral human-insulin isophane protamine human
- Ethanol + Insulin neutral human-insulin isophane protamine human Major
- Insulin neutral human-insulin isophane protamine human + Pentamidine Major
- Insulin neutral human-insulin isophane protamine human + Rosiglitazone Major
- Acarbose + Insulin neutral human-insulin isophane protamine human Moderate
- Albiglutide + Insulin neutral human-insulin isophane protamine human Moderate
- Alogliptin + Insulin neutral human-insulin isophane protamine human Moderate
Other interactions of Azilsartan
- Aliskiren + Azilsartan Contraindicated
- Azilsartan + Sparsentan Contraindicated
- Amifostine + Azilsartan Major
- Amlodipine-benazepril + Azilsartan Major
- Amlodipine-perindopril + Azilsartan Major
- Azilsartan + Benazepril Major
Frequently asked questions
Can I take Azilsartan with Insulin neutral human-insulin isophane protamine human?
MediHelp rates the interaction as minor. Azilsartan and Insulin neutral human-insulin isophane protamine human have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and can enhance the glucose-lowering effect of insulin, occasionally causing hypoglycemia. The effect is generally modest and most apparent after starting the ARB.
How serious is the interaction between Azilsartan and Insulin neutral human-insulin isophane protamine human?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently after starting or changing azilsartan and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin neutral human-insulin isophane protamine human?
MediHelp also lists interactions of Insulin neutral human-insulin isophane protamine human with, for example, Ethanol, Pentamidine, Rosiglitazone. The full list is on the Insulin neutral human-insulin isophane protamine human page.
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