Drug interactions
Azilsartan-chlorthalidone + Juniper
Severity: Minor
Azilsartan-chlorthalidone and Juniper: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Juniper has traditional diuretic activity and may add to fluid and electrolyte loss with chlorthalidone. Large amounts may irritate or damage the kidneys, which is a concern with an ARB and diuretic already affecting renal hemodynamics.
What this interaction means in plain words
Azilsartan-chlorthalidone and Juniper have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive diuretic effect from juniper volatile oils; the mechanism is not well characterized.
What to do
Advise patients to avoid juniper supplements. If used, monitor blood pressure, electrolytes and renal function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan-chlorthalidone
Frequently asked questions
Can I take Azilsartan-chlorthalidone with Juniper?
MediHelp rates the interaction as minor. Azilsartan-chlorthalidone and Juniper have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Juniper has traditional diuretic activity and may add to fluid and electrolyte loss with chlorthalidone. Large amounts may irritate or damage the kidneys, which is a concern with an ARB and diuretic already affecting renal hemodynamics.
How serious is the interaction between Azilsartan-chlorthalidone and Juniper?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid juniper supplements. If used, monitor blood pressure, electrolytes and renal function.
What other medicines interact with Azilsartan-chlorthalidone?
MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.
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