Drug interactions
Azithromycin + Epinephrine racemic
Severity: Minor
Azithromycin and Epinephrine racemic: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Racemic epinephrine is a sympathomimetic that may provoke arrhythmias and lower potassium, and azithromycin can prolong the QT interval. The clinical significance of inhaled use is likely small but may matter in susceptible patients.
What this interaction means in plain words
Azithromycin and Epinephrine racemic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive proarrhythmic and QT effects; evidence is limited.
What to do
No routine action is needed. Monitor heart rhythm in patients with known QT prolongation or cardiac disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Frequently asked questions
Can I take Azithromycin with Epinephrine racemic?
MediHelp rates the interaction as minor. Azithromycin and Epinephrine racemic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Racemic epinephrine is a sympathomimetic that may provoke arrhythmias and lower potassium, and azithromycin can prolong the QT interval. The clinical significance of inhaled use is likely small but may matter in susceptible patients.
How serious is the interaction between Azithromycin and Epinephrine racemic?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor heart rhythm in patients with known QT prolongation or cardiac disease.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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