Drug interactions
Azithromycin + Olodaterol inhaled
Severity: Moderate
Azithromycin and Olodaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Long-acting beta2 agonists can cause tachycardia, hypokalemia and QT changes, and azithromycin has QT-prolonging potential. Together they may modestly increase the risk of ventricular arrhythmia in susceptible patients.
What this interaction means in plain words
Azithromycin and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive cardiac repolarization effects with beta2-agonist-induced hypokalemia.
What to do
Monitor potassium and consider an ECG in patients with cardiac risk factors. Ask patients to report palpitations or fainting.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Frequently asked questions
Can I take Azithromycin with Olodaterol inhaled?
MediHelp rates the interaction as moderate. Azithromycin and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Long-acting beta2 agonists can cause tachycardia, hypokalemia and QT changes, and azithromycin has QT-prolonging potential. Together they may modestly increase the risk of ventricular arrhythmia in susceptible patients.
How serious is the interaction between Azithromycin and Olodaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and consider an ECG in patients with cardiac risk factors. Ask patients to report palpitations or fainting.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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