Drug interactions
Azithromycin + Temocillin
Severity: Minor
Azithromycin and Temocillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azithromycin may theoretically reduce the bactericidal activity of temocillin because it is bacteriostatic. Clinical relevance is unproven.
What this interaction means in plain words
Azithromycin and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic antagonism between a protein synthesis inhibitor and a beta-lactam.
What to do
No routine change is needed. Monitor clinical response in serious infections.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Frequently asked questions
Can I take Azithromycin with Temocillin?
MediHelp rates the interaction as minor. Azithromycin and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Azithromycin may theoretically reduce the bactericidal activity of temocillin because it is bacteriostatic. Clinical relevance is unproven.
How serious is the interaction between Azithromycin and Temocillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor clinical response in serious infections.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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