Drug interactions
Bacitracin + Tenofovir disoproxil
Severity: Major
Bacitracin and Tenofovir disoproxil: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic bacitracin is strongly nephrotoxic, and tenofovir disoproxil can also injure the renal tubules. Combined use raises the risk of acute kidney injury.
What this interaction means in plain words
Bacitracin and Tenofovir disoproxil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Additive nephrotoxicity.
What to do
Avoid concurrent use; choose a non-nephrotoxic alternative. If unavoidable, monitor serum creatinine and urine output closely.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Bacitracin
- Bacitracin + Cidofovir Contraindicated
- Adefovir + Bacitracin Major
- Aldesleukin + Bacitracin Major
- Amikacin + Bacitracin Major
- Bacitracin + Carboplatin Major
- Bacitracin + Cisplatin Major
Frequently asked questions
Can I take Bacitracin with Tenofovir disoproxil?
MediHelp rates the interaction as major. Bacitracin and Tenofovir disoproxil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic bacitracin is strongly nephrotoxic, and tenofovir disoproxil can also injure the renal tubules. Combined use raises the risk of acute kidney injury.
How serious is the interaction between Bacitracin and Tenofovir disoproxil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; choose a non-nephrotoxic alternative. If unavoidable, monitor serum creatinine and urine output closely.
What other medicines interact with Bacitracin?
MediHelp also lists interactions of Bacitracin with, for example, Cidofovir, Adefovir, Aldesleukin. The full list is on the Bacitracin page.
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