Drug interactions
Bacitracin + Cidofovir
Severity: Contraindicated
Bacitracin and Cidofovir: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cidofovir causes dose-related proximal tubular injury, and systemic bacitracin is also nephrotoxic. Together they can cause severe, potentially irreversible kidney damage.
What this interaction means in plain words
Bacitracin and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Bacitracin belongs to Miscellaneous; Cidofovir belongs to Anti Virals.
Why it happens
Additive nephrotoxicity affecting the proximal renal tubule.
What to do
Avoid the combination, since cidofovir labeling prohibits other nephrotoxic agents. Choose an alternative to one drug, and if unavoidable, stop the nephrotoxin well before cidofovir and monitor creatinine.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Cidofovir
- Amikacin + Cidofovir Contraindicated
- Amphotericin b deoxycholate + Cidofovir Contraindicated
- Amphotericin b + Cidofovir Contraindicated
- Capreomycin + Cidofovir Contraindicated
- Cephaloridine + Cidofovir Contraindicated
- Cidofovir + Cisplatin Contraindicated
Other interactions of Bacitracin
- Adefovir + Bacitracin Major
- Aldesleukin + Bacitracin Major
- Amikacin + Bacitracin Major
- Bacitracin + Carboplatin Major
- Bacitracin + Cisplatin Major
- Bacitracin + Colistin Major
Frequently asked questions
Can I take Bacitracin with Cidofovir?
MediHelp rates the interaction as contraindicated. Bacitracin and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cidofovir causes dose-related proximal tubular injury, and systemic bacitracin is also nephrotoxic. Together they can cause severe, potentially irreversible kidney damage.
How serious is the interaction between Bacitracin and Cidofovir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination, since cidofovir labeling prohibits other nephrotoxic agents. Choose an alternative to one drug, and if unavoidable, stop the nephrotoxin well before cidofovir and monitor creatinine.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
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