Drug interactions
Bacitracin-neomycin-polymyxin + Foscarnet
Severity: Moderate
Bacitracin-neomycin-polymyxin and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Foscarnet is strongly nephrotoxic, and neomycin, polymyxin B and bacitracin can add to renal injury if absorbed systemically through large wounds or burns. With limited topical use the risk is small.
What this interaction means in plain words
Bacitracin-neomycin-polymyxin and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bacitracin-neomycin-polymyxin belongs to Anti Bacterial; Foscarnet belongs to Anti Virals.
Why it happens
Additive nephrotoxicity when systemic absorption of the topical antibiotics occurs.
What to do
Avoid large-area or prolonged application during foscarnet therapy. Monitor serum creatinine and electrolytes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Bacitracin-neomycin-polymyxin and Foscarnet, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Bacitracin-neomycin-polymyxin
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin Major
- Atracurium + Bacitracin-neomycin-polymyxin Major
- Bacitracin-neomycin-polymyxin + Capreomycin Major
- Bacitracin-neomycin-polymyxin + Cidofovir Major
- Bacitracin-neomycin-polymyxin + Cisatracurium Major
- Bacitracin-neomycin-polymyxin + Pancuronium Major
Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Bacitracin-neomycin-polymyxin with Foscarnet?
MediHelp rates the interaction as moderate. Bacitracin-neomycin-polymyxin and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Foscarnet is strongly nephrotoxic, and neomycin, polymyxin B and bacitracin can add to renal injury if absorbed systemically through large wounds or burns. With limited topical use the risk is small.
How serious is the interaction between Bacitracin-neomycin-polymyxin and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid large-area or prolonged application during foscarnet therapy. Monitor serum creatinine and electrolytes.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Allogeneic cultured keratinocytes / fibroblasts in bovine collagen, Atracurium, Capreomycin. The full list is on the Bacitracin-neomycin-polymyxin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
