Drug interactions
Basiliximab + Rozanolixizumab
Severity: Moderate
Basiliximab and Rozanolixizumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rozanolixizumab blocks the neonatal Fc receptor and increases IgG clearance, which could reduce basiliximab exposure and weaken IL-2 receptor blockade.
What this interaction means in plain words
Basiliximab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Rozanolixizumab belongs to Miscellaneous.
Why it happens
FcRn blockade reduces IgG recycling and accelerates clearance of IgG monoclonal antibodies.
What to do
Avoid giving rozanolixizumab around basiliximab dosing when possible and monitor for graft rejection or loss of effect.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Other interactions of Rozanolixizumab
- Rozanolixizumab + Upadacitinib Major
- Abatacept + Rozanolixizumab Moderate
- Adalimumab + Rozanolixizumab Moderate
- Ado-trastuzumab + Rozanolixizumab Moderate
- Bevacizumab + Rozanolixizumab Moderate
- Denosumab + Rozanolixizumab Moderate
Frequently asked questions
Can I take Basiliximab with Rozanolixizumab?
MediHelp rates the interaction as moderate. Basiliximab and Rozanolixizumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rozanolixizumab blocks the neonatal Fc receptor and increases IgG clearance, which could reduce basiliximab exposure and weaken IL-2 receptor blockade.
How serious is the interaction between Basiliximab and Rozanolixizumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving rozanolixizumab around basiliximab dosing when possible and monitor for graft rejection or loss of effect.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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