Drug interactions
Basiliximab + Trastuzumab
Severity: Moderate
Basiliximab and Trastuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab causes immunosuppression, while trastuzumab, mainly with myelosuppressive chemotherapy, is associated with neutropenia. Together they may raise infection risk, although direct data for this pair are scarce.
What this interaction means in plain words
Basiliximab and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Trastuzumab belongs to Oncology.
Why it happens
Possible additive effects on immune defence; no specific pharmacokinetic interaction is established.
What to do
Monitor for infection and check neutrophil counts, especially if myelosuppressive chemotherapy is also given. Treat fever promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Other interactions of Trastuzumab
Frequently asked questions
Can I take Basiliximab with Trastuzumab?
MediHelp rates the interaction as moderate. Basiliximab and Trastuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab causes immunosuppression, while trastuzumab, mainly with myelosuppressive chemotherapy, is associated with neutropenia. Together they may raise infection risk, although direct data for this pair are scarce.
How serious is the interaction between Basiliximab and Trastuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for infection and check neutrophil counts, especially if myelosuppressive chemotherapy is also given. Treat fever promptly.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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