Drug interactions
Basiliximab + Ublituximab
Severity: Moderate
Basiliximab and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Basiliximab inhibits T-cell activation and ublituximab depletes B cells, so together they add to immunosuppression. This increases the risk of serious infections.
What this interaction means in plain words
Basiliximab and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Basiliximab belongs to Miscellaneous; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from IL-2 receptor blockade and anti-CD20 B-cell depletion.
What to do
Monitor closely for infection and screen for hepatitis B before ublituximab. Take the prolonged effect of B-cell depletion into account when planning other immunosuppressants.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Basiliximab and Ublituximab, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Measles vaccine Contraindicated
Other interactions of Ublituximab
Frequently asked questions
Can I take Basiliximab with Ublituximab?
MediHelp rates the interaction as moderate. Basiliximab and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Basiliximab inhibits T-cell activation and ublituximab depletes B cells, so together they add to immunosuppression. This increases the risk of serious infections.
How serious is the interaction between Basiliximab and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor closely for infection and screen for hepatitis B before ublituximab. Take the prolonged effect of B-cell depletion into account when planning other immunosuppressants.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
