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Drug interactions

Bcg vaccine live + Meropenem

Severity: Minor

Bcg vaccine live and Meropenem: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Live BCG is a viable bacterial vaccine, and an antibiotic active against it could reduce its replication and weaken the immune response. Meropenem has limited activity against BCG, so the effect is largely theoretical.

What this interaction means in plain words

Bcg vaccine live and Meropenem have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical antibacterial activity against the live vaccine organism; BCG is generally not susceptible to meropenem.

What to do

No routine delay is needed for BCG with meropenem; vaccinate on schedule unless the patient is acutely and severely ill.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bcg vaccine live with Meropenem?

MediHelp rates the interaction as minor. Bcg vaccine live and Meropenem have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Live BCG is a viable bacterial vaccine, and an antibiotic active against it could reduce its replication and weaken the immune response. Meropenem has limited activity against BCG, so the effect is largely theoretical.

How serious is the interaction between Bcg vaccine live and Meropenem?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine delay is needed for BCG with meropenem; vaccinate on schedule unless the patient is acutely and severely ill.

What other medicines interact with Meropenem?

MediHelp also lists interactions of Meropenem with, for example, Valproic acid, Typhoid vaccine live, Amifampridine. The full list is on the Meropenem page.

Full monographs, dosing and an interaction checker in the MediHelp app

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