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Drug interactions

Beclomethasone inhaled + Enalapril-hydrochlorothiazide

Severity: Minor

Beclomethasone inhaled and Enalapril-hydrochlorothiazide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Systemic corticosteroids increase potassium loss with thiazides, but inhaled beclomethasone has low systemic exposure at usual doses. Clinically relevant hypokalemia is unlikely.

What this interaction means in plain words

Beclomethasone inhaled and Enalapril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Minimal mineralocorticoid effect from low systemic absorption, additive to thiazide potassium loss.

What to do

No routine action; check potassium if high-dose inhaled steroid is used with other potassium-lowering drugs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Beclomethasone inhaled with Enalapril-hydrochlorothiazide?

MediHelp rates the interaction as minor. Beclomethasone inhaled and Enalapril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids increase potassium loss with thiazides, but inhaled beclomethasone has low systemic exposure at usual doses. Clinically relevant hypokalemia is unlikely.

How serious is the interaction between Beclomethasone inhaled and Enalapril-hydrochlorothiazide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; check potassium if high-dose inhaled steroid is used with other potassium-lowering drugs.

What other medicines interact with Enalapril-hydrochlorothiazide?

MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.

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