Drug interactions
Beclomethasone inhaled + Hydrochlorothiazide-losartan
Severity: Minor
Beclomethasone inhaled and Hydrochlorothiazide-losartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids can increase potassium loss, so inhaled beclomethasone may add to thiazide-induced hypokalemia. With inhaled dosing at usual doses, systemic exposure is low and the effect is small.
What this interaction means in plain words
Beclomethasone inhaled and Hydrochlorothiazide-losartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mineralocorticoid-like potassium wasting from systemically absorbed corticosteroid adds to thiazide kaliuresis.
What to do
Monitor serum potassium if high inhaled doses or additional potassium-lowering drugs are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-losartan
- Aliskiren + Hydrochlorothiazide-losartan Contraindicated
- Dofetilide + Hydrochlorothiazide-losartan Contraindicated
- Hydrochlorothiazide-losartan + Sparsentan Contraindicated
- Aceclofenac + Hydrochlorothiazide-losartan Major
- Aldesleukin + Hydrochlorothiazide-losartan Major
- Amifostine + Hydrochlorothiazide-losartan Major
Frequently asked questions
Can I take Beclomethasone inhaled with Hydrochlorothiazide-losartan?
MediHelp rates the interaction as minor. Beclomethasone inhaled and Hydrochlorothiazide-losartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids can increase potassium loss, so inhaled beclomethasone may add to thiazide-induced hypokalemia. With inhaled dosing at usual doses, systemic exposure is low and the effect is small.
How serious is the interaction between Beclomethasone inhaled and Hydrochlorothiazide-losartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if high inhaled doses or additional potassium-lowering drugs are used.
What other medicines interact with Hydrochlorothiazide-losartan?
MediHelp also lists interactions of Hydrochlorothiazide-losartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-losartan page.
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