Drug interactions
Bemiparin + Celecoxib
Severity: Moderate
Bemiparin and Celecoxib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bemiparin is a low-molecular-weight heparin, and NSAIDs increase bleeding risk with heparins through gastrointestinal injury and platelet effects. Celecoxib has less platelet effect than nonselective NSAIDs but the risk is still relevant.
What this interaction means in plain words
Bemiparin and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive effects on hemostasis: anti-Xa anticoagulation plus NSAID mucosal and platelet effects.
What to do
Avoid unnecessary NSAID use during heparin therapy and prefer paracetamol. If combined, monitor for bleeding and hemoglobin, and consider gastroprotection.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Bemiparin with Celecoxib?
MediHelp rates the interaction as moderate. Bemiparin and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bemiparin is a low-molecular-weight heparin, and NSAIDs increase bleeding risk with heparins through gastrointestinal injury and platelet effects. Celecoxib has less platelet effect than nonselective NSAIDs but the risk is still relevant.
How serious is the interaction between Bemiparin and Celecoxib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary NSAID use during heparin therapy and prefer paracetamol. If combined, monitor for bleeding and hemoglobin, and consider gastroprotection.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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