Drug interactions
Benazepril + Creatine
Severity: Minor
Benazepril and Creatine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Creatine can raise serum creatinine and has been theorized to add renal stress, while ACE inhibitors reduce glomerular filtration pressure. Evidence of harm is limited, but renal markers may be harder to interpret.
What this interaction means in plain words
Benazepril and Creatine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive renal effects; creatine raises creatinine independent of true GFR change.
What to do
Monitor serum creatinine and potassium periodically and avoid creatine in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Frequently asked questions
Can I take Benazepril with Creatine?
MediHelp rates the interaction as minor. Benazepril and Creatine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Creatine can raise serum creatinine and has been theorized to add renal stress, while ACE inhibitors reduce glomerular filtration pressure. Evidence of harm is limited, but renal markers may be harder to interpret.
How serious is the interaction between Benazepril and Creatine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and potassium periodically and avoid creatine in patients with renal impairment.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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