Drug interactions
Benazepril + Exenatide injectable
Severity: Minor
Benazepril and Exenatide injectable: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors may improve insulin sensitivity and modestly enhance the glucose lowering of antidiabetic drugs. Hypoglycemia is mainly a concern when exenatide is combined with other agents such as sulfonylureas or insulin.
What this interaction means in plain words
Benazepril and Exenatide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
ACE inhibition may increase insulin sensitivity and bradykinin-mediated glucose uptake, adding to incretin-mediated glucose lowering.
What to do
Monitor blood glucose when benazepril is started, especially if the patient also takes insulin or a sulfonylureas. Adjust the dose of the other antidiabetic agents if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Frequently asked questions
Can I take Benazepril with Exenatide injectable?
MediHelp rates the interaction as minor. Benazepril and Exenatide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors may improve insulin sensitivity and modestly enhance the glucose lowering of antidiabetic drugs. Hypoglycemia is mainly a concern when exenatide is combined with other agents such as sulfonylureas or insulin.
How serious is the interaction between Benazepril and Exenatide injectable?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when benazepril is started, especially if the patient also takes insulin or a sulfonylureas. Adjust the dose of the other antidiabetic agents if hypoglycemia occurs.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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