Drug interactions
Benazepril + Insulin neutral human
Severity: Moderate
Benazepril and Insulin neutral human: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors can enhance insulin sensitivity and may increase the hypoglycemic effect of insulin. Cases of hypoglycemia have been reported, mainly after ACE inhibitor initiation in insulin-treated patients.
What this interaction means in plain words
Benazepril and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Insulin neutral human belongs to Endocrine.
Why it happens
ACE inhibition raises bradykinin levels and may improve insulin sensitivity and glucose uptake in peripheral tissues.
What to do
Monitor blood glucose more frequently when benazepril is started, especially in the first weeks. Lower the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin neutral human
Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Frequently asked questions
Can I take Benazepril with Insulin neutral human?
MediHelp rates the interaction as moderate. Benazepril and Insulin neutral human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. ACE inhibitors can enhance insulin sensitivity and may increase the hypoglycemic effect of insulin. Cases of hypoglycemia have been reported, mainly after ACE inhibitor initiation in insulin-treated patients.
How serious is the interaction between Benazepril and Insulin neutral human?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when benazepril is started, especially in the first weeks. Lower the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin neutral human?
MediHelp also lists interactions of Insulin neutral human with, for example, Chlorpropamide, Ethanol, Mecasermin. The full list is on the Insulin neutral human page.
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