Drug interactions
Benazepril + Nitric oxide gas
Severity: Minor
Benazepril and Nitric oxide gas: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled nitric oxide is a pulmonary vasodilator and ACE inhibitors lower systemic vascular resistance. Together they may add to blood pressure lowering, although systemic effects of inhaled nitric oxide are usually small.
What this interaction means in plain words
Benazepril and Nitric oxide gas have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive vasodilatory pharmacodynamic effects.
What to do
Monitor blood pressure when inhaled nitric oxide is started or stopped in a patient taking benazepril.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Frequently asked questions
Can I take Benazepril with Nitric oxide gas?
MediHelp rates the interaction as minor. Benazepril and Nitric oxide gas have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled nitric oxide is a pulmonary vasodilator and ACE inhibitors lower systemic vascular resistance. Together they may add to blood pressure lowering, although systemic effects of inhaled nitric oxide are usually small.
How serious is the interaction between Benazepril and Nitric oxide gas?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when inhaled nitric oxide is started or stopped in a patient taking benazepril.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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