Drug interactions
Benazepril + Sodium bicarbonate
Severity: Minor
Benazepril and Sodium bicarbonate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
A clinically meaningful interaction is not well established, and any effect on benazepril efficacy is unproven. Sodium bicarbonate does supply a sodium load that could modestly oppose blood pressure control.
What this interaction means in plain words
Benazepril and Sodium bicarbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benazepril belongs to Cardiovascular; Sodium bicarbonate belongs to Gastrointestinal Tract.
Why it happens
No established mechanism; sodium load may theoretically oppose antihypertensive effect.
What to do
No specific action is needed beyond monitoring blood pressure in patients taking large or regular doses of bicarbonate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Sodium bicarbonate
- Acetylsalicylic acid + Sodium bicarbonate Moderate
- Alendronate + Sodium bicarbonate Moderate
- Amantadine + Sodium bicarbonate Moderate
- Carbonyl iron + Sodium bicarbonate Moderate
- Cefditoren + Sodium bicarbonate Moderate
- Cefpodoxime + Sodium bicarbonate Moderate
Frequently asked questions
Can I take Benazepril with Sodium bicarbonate?
MediHelp rates the interaction as minor. Benazepril and Sodium bicarbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. A clinically meaningful interaction is not well established, and any effect on benazepril efficacy is unproven. Sodium bicarbonate does supply a sodium load that could modestly oppose blood pressure control.
How serious is the interaction between Benazepril and Sodium bicarbonate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond monitoring blood pressure in patients taking large or regular doses of bicarbonate.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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