Drug interactions
Benazepril + Synthetic human angiotensin ii
Severity: Moderate
Benazepril and Synthetic human angiotensin ii: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Patients on ACE inhibitors may have an exaggerated pressor response to angiotensin II, because its production is blocked and receptor sensitivity increases. Lower starting doses of angiotensin II are recommended in these patients.
What this interaction means in plain words
Benazepril and Synthetic human angiotensin ii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
ACE inhibition reduces endogenous angiotensin II, so exogenous angiotensin II acts on a more responsive system and can produce greater pressor effects.
What to do
Start angiotensin II at the low end of the dosing range and titrate to blood pressure with continuous monitoring.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Frequently asked questions
Can I take Benazepril with Synthetic human angiotensin ii?
MediHelp rates the interaction as moderate. Benazepril and Synthetic human angiotensin ii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patients on ACE inhibitors may have an exaggerated pressor response to angiotensin II, because its production is blocked and receptor sensitivity increases. Lower starting doses of angiotensin II are recommended in these patients.
How serious is the interaction between Benazepril and Synthetic human angiotensin ii?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start angiotensin II at the low end of the dosing range and titrate to blood pressure with continuous monitoring.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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