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Drug interactions

Bendroflumethiazide + Formoterol-mometasone

Severity: Moderate

Bendroflumethiazide and Formoterol-mometasone: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Thiazide diuretics cause potassium loss, and beta-2 agonists can further lower serum potassium. The additive hypokalemia may provoke arrhythmias, especially with high-dose formoterol or heart disease.

What this interaction means in plain words

Bendroflumethiazide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Moderate

Why it happens

Additive hypokalemia through renal potassium loss and beta-2-mediated cellular potassium uptake.

What to do

Monitor serum potassium and replace if low. Use extra care in patients with cardiac disease or on digoxin.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bendroflumethiazide with Formoterol-mometasone?

MediHelp rates the interaction as moderate. Bendroflumethiazide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide diuretics cause potassium loss, and beta-2 agonists can further lower serum potassium. The additive hypokalemia may provoke arrhythmias, especially with high-dose formoterol or heart disease.

How serious is the interaction between Bendroflumethiazide and Formoterol-mometasone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace if low. Use extra care in patients with cardiac disease or on digoxin.

What other medicines interact with Formoterol-mometasone?

MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.

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