Drug interactions
Berotralstat + Dipyridamole
Severity: Minor
Berotralstat and Dipyridamole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole inhibits BCRP and may raise berotralstat exposure. This could increase berotralstat adverse effects such as gastrointestinal upset.
What this interaction means in plain words
Berotralstat and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Berotralstat belongs to Miscellaneous; Dipyridamole belongs to Cardiovascular.
Why it happens
Inhibition of BCRP-mediated efflux by dipyridamole may increase berotralstat absorption and exposure.
What to do
Monitor for berotralstat adverse effects, particularly gastrointestinal symptoms and QT-related symptoms at higher exposure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Berotralstat
- Berotralstat + Ergotamine Major
- Berotralstat + Nilotinib Major
- Berotralstat + Pimozide Major
- Berotralstat + Quinidine Major
- Berotralstat + Quinine Major
- Berotralstat + Tacrolimus Major
Frequently asked questions
Can I take Berotralstat with Dipyridamole?
MediHelp rates the interaction as minor. Berotralstat and Dipyridamole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dipyridamole inhibits BCRP and may raise berotralstat exposure. This could increase berotralstat adverse effects such as gastrointestinal upset.
How serious is the interaction between Berotralstat and Dipyridamole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for berotralstat adverse effects, particularly gastrointestinal symptoms and QT-related symptoms at higher exposure.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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