Drug interactions
Betaxolol + Ciprofloxacin
Severity: Minor
Betaxolol and Ciprofloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol is metabolized partly by CYP1A2, which ciprofloxacin inhibits strongly. Exposure to betaxolol could rise, but the effect is likely small, as the drug also has renal elimination and other pathways. Excess beta-blockade would present as bradycardia or hypotension.
What this interaction means in plain words
Betaxolol and Ciprofloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Ciprofloxacin belongs to Anti Bacterial.
Why it happens
Possible inhibition of CYP1A2-mediated betaxolol metabolism by ciprofloxacin.
What to do
Monitor heart rate and blood pressure when starting or stopping ciprofloxacin. Reduce the betaxolol dose if bradycardia or hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Ciprofloxacin?
MediHelp rates the interaction as minor. Betaxolol and Ciprofloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Betaxolol is metabolized partly by CYP1A2, which ciprofloxacin inhibits strongly. Exposure to betaxolol could rise, but the effect is likely small, as the drug also has renal elimination and other pathways. Excess beta-blockade would present as bradycardia or hypotension.
How serious is the interaction between Betaxolol and Ciprofloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when starting or stopping ciprofloxacin. Reduce the betaxolol dose if bradycardia or hypotension occurs.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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