Drug interactions
Betaxolol + Nimodipine
Severity: Moderate
Betaxolol and Nimodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nimodipine can lower blood pressure significantly, and concurrent betaxolol may increase this effect. This matters particularly in subarachnoid hemorrhage, where hypotension may compromise cerebral perfusion.
What this interaction means in plain words
Betaxolol and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Betaxolol belongs to Cardiovascular; Nimodipine belongs to Cardiovascular.
Why it happens
Additive hypotensive effects from calcium channel blockade and beta-adrenergic blockade.
What to do
Monitor blood pressure closely, and reduce the nimodipine dose or split dosing if hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Betaxolol with Nimodipine?
MediHelp rates the interaction as moderate. Betaxolol and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nimodipine can lower blood pressure significantly, and concurrent betaxolol may increase this effect. This matters particularly in subarachnoid hemorrhage, where hypotension may compromise cerebral perfusion.
How serious is the interaction between Betaxolol and Nimodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely, and reduce the nimodipine dose or split dosing if hypotension occurs.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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