Drug interactions
Bexarotene + Insulin glargine-lixisenatide
Severity: Minor
Bexarotene and Insulin glargine-lixisenatide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bexarotene, a retinoid X receptor agonist, may improve insulin sensitivity and has been associated with enhanced glucose lowering in diabetic patients. Hypoglycemia is possible with insulin.
What this interaction means in plain words
Bexarotene and Insulin glargine-lixisenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bexarotene belongs to Oncology; Insulin glargine-lixisenatide belongs to Endocrine.
Why it happens
RXR activation may enhance insulin sensitivity, adding to insulin action.
What to do
Monitor blood glucose when bexarotene is started. Reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin glargine-lixisenatide
- Albiglutide + Insulin glargine-lixisenatide Major
- Chlorpropamide + Insulin glargine-lixisenatide Major
- Dulaglutide + Insulin glargine-lixisenatide Major
- Ethanol + Insulin glargine-lixisenatide Major
- Exenatide injectable + Insulin glargine-lixisenatide Major
- Glimepiride + Insulin glargine-lixisenatide Major
Other interactions of Bexarotene
- Bexarotene + Gemfibrozil Major
- Bexarotene + Lorlatinib Major
- Alogliptin-pioglitazone + Bexarotene Moderate
- Amobarbital + Bexarotene Moderate
- Aprepitant + Bexarotene Moderate
- Axitinib + Bexarotene Moderate
Frequently asked questions
Can I take Bexarotene with Insulin glargine-lixisenatide?
MediHelp rates the interaction as minor. Bexarotene and Insulin glargine-lixisenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bexarotene, a retinoid X receptor agonist, may improve insulin sensitivity and has been associated with enhanced glucose lowering in diabetic patients. Hypoglycemia is possible with insulin.
How serious is the interaction between Bexarotene and Insulin glargine-lixisenatide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when bexarotene is started. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
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