Drug interactions
Bimatoprost + Ketorolac
Severity: Minor
Bimatoprost and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Data on how systemic NSAIDs affect the intraocular pressure response to ophthalmic prostaglandin analogues are conflicting. No consistent clinically important effect with systemic ketorolac has been established.
What this interaction means in plain words
Bimatoprost and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bimatoprost belongs to Miscellaneous; Ketorolac belongs to Musculoskeletal.
Why it happens
Mechanism is not established; prostaglandin-mediated pathways in aqueous humor dynamics may be altered by NSAIDs.
What to do
No routine change is needed. Check intraocular pressure at usual follow-up visits if an NSAID is used for a prolonged period.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Bimatoprost
- Bimatoprost + Latanoprost Moderate
- Bimatoprost + Latanoprostene bunod Moderate
- Bimatoprost + Tafluprost Moderate
- Bimatoprost + Travoprost Moderate
- Aspirin rectal + Bimatoprost Minor
- Aspirin + Bimatoprost Minor
Frequently asked questions
Can I take Bimatoprost with Ketorolac?
MediHelp rates the interaction as minor. Bimatoprost and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Data on how systemic NSAIDs affect the intraocular pressure response to ophthalmic prostaglandin analogues are conflicting. No consistent clinically important effect with systemic ketorolac has been established.
How serious is the interaction between Bimatoprost and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Check intraocular pressure at usual follow-up visits if an NSAID is used for a prolonged period.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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