Drug interactions
Bisoprolol + Captopril-hydrochlorothiazide
Severity: Minor
Bisoprolol and Captopril-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bisoprolol with captopril-hydrochlorothiazide is a common combination with additive blood pressure lowering. Hypotension or bradycardia may occur, and no significant potassium interaction is expected.
What this interaction means in plain words
Bisoprolol and Captopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Bisoprolol belongs to Cardiovascular; Captopril-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Additive antihypertensive effect from beta-blockade, ACE inhibition and diuresis.
What to do
Monitor blood pressure and heart rate when starting or adjusting therapy. Reduce doses if symptomatic hypotension or bradycardia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Other interactions of Bisoprolol
Frequently asked questions
Can I take Bisoprolol with Captopril-hydrochlorothiazide?
MediHelp rates the interaction as minor. Bisoprolol and Captopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bisoprolol with captopril-hydrochlorothiazide is a common combination with additive blood pressure lowering. Hypotension or bradycardia may occur, and no significant potassium interaction is expected.
How serious is the interaction between Bisoprolol and Captopril-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting therapy. Reduce doses if symptomatic hypotension or bradycardia occurs.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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