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Drug interactions

Bisoprolol + Formoterol-mometasone

Severity: Moderate

Bisoprolol and Formoterol-mometasone: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Bisoprolol can oppose the bronchodilating action of formoterol and may worsen bronchospasm in patients with asthma or COPD. Its high beta-1 selectivity makes this less likely than with nonselective agents, particularly at low doses.

What this interaction means in plain words

Bisoprolol and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Bisoprolol belongs to Cardiovascular; Formoterol-mometasone belongs to Respiratory.

Evidence level: High

Why it happens

Competitive pharmacodynamic antagonism at beta-adrenergic receptors.

What to do

Start bisoprolol at a low dose and monitor respiratory symptoms and lung function. Reassess the need for the beta-blocker if bronchospasm or reduced formoterol response occurs.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Bisoprolol with Formoterol-mometasone?

MediHelp rates the interaction as moderate. Bisoprolol and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bisoprolol can oppose the bronchodilating action of formoterol and may worsen bronchospasm in patients with asthma or COPD. Its high beta-1 selectivity makes this less likely than with nonselective agents, particularly at low doses.

How serious is the interaction between Bisoprolol and Formoterol-mometasone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start bisoprolol at a low dose and monitor respiratory symptoms and lung function. Reassess the need for the beta-blocker if bronchospasm or reduced formoterol response occurs.

What other medicines interact with Formoterol-mometasone?

MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.

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