Drug interactions
Bivalirudin + Cefazolin
Severity: Minor
Bivalirudin and Cefazolin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefazolin is not known to meaningfully potentiate bivalirudin; any additive bleeding effect is theoretical.
What this interaction means in plain words
Bivalirudin and Cefazolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; only a theoretical additive effect on hemostasis.
What to do
No specific action beyond routine bleeding and ACT monitoring during bivalirudin therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefazolin
- Amikacin + Cefazolin Moderate
- Bcg vaccine live + Cefazolin Moderate
- Cefazolin + Cholera vaccine Moderate
- Cefazolin + Dexamethasone-tobramycin Moderate
- Cefazolin + Gentamicin Moderate
- Cefazolin + Kanamycin Moderate
Frequently asked questions
Can I take Bivalirudin with Cefazolin?
MediHelp rates the interaction as minor. Bivalirudin and Cefazolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefazolin is not known to meaningfully potentiate bivalirudin; any additive bleeding effect is theoretical.
How serious is the interaction between Bivalirudin and Cefazolin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action beyond routine bleeding and ACT monitoring during bivalirudin therapy.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
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