Drug interactions
Bosentan + Shepherd's purse
Severity: Minor
Bosentan and Shepherd's purse: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shepherd's purse has been theoretically linked to effects on blood pressure, which could oppose the vasodilatory action of bosentan. No clinical reports confirm a meaningful interaction.
What this interaction means in plain words
Bosentan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic effect on blood pressure; mechanism not established.
What to do
Monitor blood pressure and pulmonary hypertension symptoms if the herb is used. Advise patients to discuss herbal products first.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Bosentan
- Bosentan + Cyclosporin Contraindicated
- Bosentan + Glibenclamide Contraindicated
- Bosentan + Glyburide-metformin Contraindicated
- Bosentan + Lonafarnib Contraindicated
- Bosentan + Sparsentan Contraindicated
- Artemether / lumefantrine + Bosentan Major
Frequently asked questions
Can I take Bosentan with Shepherd's purse?
MediHelp rates the interaction as minor. Bosentan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been theoretically linked to effects on blood pressure, which could oppose the vasodilatory action of bosentan. No clinical reports confirm a meaningful interaction.
How serious is the interaction between Bosentan and Shepherd's purse?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and pulmonary hypertension symptoms if the herb is used. Advise patients to discuss herbal products first.
What other medicines interact with Bosentan?
MediHelp also lists interactions of Bosentan with, for example, Cyclosporin, Glibenclamide, Glyburide-metformin. The full list is on the Bosentan page.
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