Drug interactions
Brivaracetam + Chlordiazepoxide-clidinium
Severity: Moderate
Brivaracetam and Chlordiazepoxide-clidinium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brivaracetam commonly causes somnolence and dizziness, which may be additive with chlordiazepoxide. This can impair alertness and coordination.
What this interaction means in plain words
Brivaracetam and Chlordiazepoxide-clidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brivaracetam belongs to Central Nervous System; Chlordiazepoxide-clidinium belongs to Gastrointestinal Tract.
Why it happens
Additive CNS depressant effects.
What to do
Monitor for sedation, dizziness and falls, particularly when starting or titrating. Advise caution with driving.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chlordiazepoxide-clidinium
- Alfentanil + Chlordiazepoxide-clidinium Major
- Alprazolam + Chlordiazepoxide-clidinium Major
- Amobarbital + Chlordiazepoxide-clidinium Major
- Belladonna and opium + Chlordiazepoxide-clidinium Major
- Benzhydrocodone / acetaminophen + Chlordiazepoxide-clidinium Major
- Brexanolone + Chlordiazepoxide-clidinium Major
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Chlordiazepoxide-clidinium?
MediHelp rates the interaction as moderate. Brivaracetam and Chlordiazepoxide-clidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brivaracetam commonly causes somnolence and dizziness, which may be additive with chlordiazepoxide. This can impair alertness and coordination.
How serious is the interaction between Brivaracetam and Chlordiazepoxide-clidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation, dizziness and falls, particularly when starting or titrating. Advise caution with driving.
What other medicines interact with Chlordiazepoxide-clidinium?
MediHelp also lists interactions of Chlordiazepoxide-clidinium with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide-clidinium page.
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