Drug interactions
Brivaracetam + Oxymorphone
Severity: Moderate
Brivaracetam and Oxymorphone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brivaracetam commonly causes somnolence and dizziness, which may add to the sedation and psychomotor impairment of oxymorphone. The combined effect can impair alertness and increase fall risk.
What this interaction means in plain words
Brivaracetam and Oxymorphone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brivaracetam belongs to Central Nervous System; Oxymorphone belongs to Musculoskeletal.
Why it happens
Additive central nervous system depressant effects.
What to do
Use the lowest effective doses and monitor for sedation and impaired psychomotor function. Advise patients to avoid driving until the response is known.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxymorphone
- Alvimopan + Oxymorphone Contraindicated
- Ethanol + Oxymorphone Contraindicated
- Isocarboxazid + Oxymorphone Contraindicated
- Olanzapine / samidorphan + Oxymorphone Contraindicated
- Oxymorphone + Phenelzine Contraindicated
- Oxymorphone + Selegiline transdermal Contraindicated
Other interactions of Brivaracetam
Frequently asked questions
Can I take Brivaracetam with Oxymorphone?
MediHelp rates the interaction as moderate. Brivaracetam and Oxymorphone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brivaracetam commonly causes somnolence and dizziness, which may add to the sedation and psychomotor impairment of oxymorphone. The combined effect can impair alertness and increase fall risk.
How serious is the interaction between Brivaracetam and Oxymorphone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor for sedation and impaired psychomotor function. Advise patients to avoid driving until the response is known.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
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