Drug interactions
Brivaracetam + Sufentanil
Severity: Moderate
Brivaracetam and Sufentanil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Opioids such as sufentanil cause sedation and respiratory depression, and brivaracetam adds to CNS depression. The combination may produce excess drowsiness and reduced respiratory drive.
What this interaction means in plain words
Brivaracetam and Sufentanil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brivaracetam belongs to Central Nervous System; Sufentanil belongs to Musculoskeletal.
Why it happens
Additive CNS and respiratory depressant effects.
What to do
Use the lowest effective sufentanil dose and monitor sedation and respiratory rate. Reduce doses if excess sedation occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Brivaracetam
Other interactions of Sufentanil
- Alprazolam + Sufentanil Major
- Amitriptyline + Sufentanil Major
- Amobarbital + Sufentanil Major
- Aripiprazole + Sufentanil Major
- Asenapine + Sufentanil Major
- Baclofen + Sufentanil Major
Frequently asked questions
Can I take Brivaracetam with Sufentanil?
MediHelp rates the interaction as moderate. Brivaracetam and Sufentanil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Opioids such as sufentanil cause sedation and respiratory depression, and brivaracetam adds to CNS depression. The combination may produce excess drowsiness and reduced respiratory drive.
How serious is the interaction between Brivaracetam and Sufentanil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective sufentanil dose and monitor sedation and respiratory rate. Reduce doses if excess sedation occurs.
What other medicines interact with Brivaracetam?
MediHelp also lists interactions of Brivaracetam with, for example, Benzhydrocodone / acetaminophen, Sodium oxybate, Acetaminophen / phenyltoloxamine. The full list is on the Brivaracetam page.
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