Drug interactions
Brivaracetam + Tolcapone
Severity: Minor
Brivaracetam and Tolcapone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tolcapone can cause somnolence, dizziness and hallucinations, and brivaracetam can add to drowsiness. The combined effect may be additive but is usually modest.
What this interaction means in plain words
Brivaracetam and Tolcapone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Brivaracetam belongs to Central Nervous System; Tolcapone belongs to Central Nervous System.
Why it happens
Additive CNS effects; no established pharmacokinetic interaction.
What to do
Monitor for drowsiness and confusion, and counsel patients about driving and operating machinery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Brivaracetam and Tolcapone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Brivaracetam
Other interactions of Tolcapone
- Isocarboxazid + Tolcapone Contraindicated
- Phenelzine + Tolcapone Contraindicated
- Tolcapone + Tranylcypromine Contraindicated
- Metoclopramide + Tolcapone Major
- Apomorphine + Tolcapone Moderate
- Asenapine + Tolcapone Moderate
Frequently asked questions
Can I take Brivaracetam with Tolcapone?
MediHelp rates the interaction as minor. Brivaracetam and Tolcapone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tolcapone can cause somnolence, dizziness and hallucinations, and brivaracetam can add to drowsiness. The combined effect may be additive but is usually modest.
How serious is the interaction between Brivaracetam and Tolcapone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for drowsiness and confusion, and counsel patients about driving and operating machinery.
What other medicines interact with Brivaracetam?
MediHelp also lists interactions of Brivaracetam with, for example, Benzhydrocodone / acetaminophen, Sodium oxybate, Acetaminophen / phenyltoloxamine. The full list is on the Brivaracetam page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
