Drug interactions
Brompheniramine + Carisoprodol
Severity: Moderate
Brompheniramine and Carisoprodol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine is a sedating first-generation antihistamine, and combining it with carisoprodol can increase drowsiness and impair psychomotor performance. Anticholinergic effects may add to confusion in older adults.
What this interaction means in plain words
Brompheniramine and Carisoprodol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brompheniramine belongs to Respiratory; Carisoprodol belongs to Musculoskeletal.
Why it happens
Additive CNS depression from central H1-receptor blockade and carisoprodol's muscle relaxant and sedative action.
What to do
Advise avoiding driving and alcohol, and consider a non-sedating antihistamine if one is needed. Monitor older patients for confusion and falls.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carisoprodol
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Carisoprodol?
MediHelp rates the interaction as moderate. Brompheniramine and Carisoprodol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brompheniramine is a sedating first-generation antihistamine, and combining it with carisoprodol can increase drowsiness and impair psychomotor performance. Anticholinergic effects may add to confusion in older adults.
How serious is the interaction between Brompheniramine and Carisoprodol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding driving and alcohol, and consider a non-sedating antihistamine if one is needed. Monitor older patients for confusion and falls.
What other medicines interact with Carisoprodol?
MediHelp also lists interactions of Carisoprodol with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Carisoprodol page.
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