Drug interactions
Brompheniramine + Lormetazepam
Severity: Moderate
Brompheniramine and Lormetazepam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Brompheniramine and lormetazepam both cause sedation. Taken together they may produce marked drowsiness, impaired psychomotor function and increased fall risk, particularly in older adults.
What this interaction means in plain words
Brompheniramine and Lormetazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression through H1 antagonism and enhanced GABA-A receptor activity.
What to do
Advise against driving and alcohol use, and use the lowest effective lormetazepam dose. Prefer a non-sedating antihistamine where an antihistamine is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Brompheniramine and Lormetazepam, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Brompheniramine
Frequently asked questions
Can I take Brompheniramine with Lormetazepam?
MediHelp rates the interaction as moderate. Brompheniramine and Lormetazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brompheniramine and lormetazepam both cause sedation. Taken together they may produce marked drowsiness, impaired psychomotor function and increased fall risk, particularly in older adults.
How serious is the interaction between Brompheniramine and Lormetazepam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise against driving and alcohol use, and use the lowest effective lormetazepam dose. Prefer a non-sedating antihistamine where an antihistamine is needed.
What other medicines interact with Brompheniramine?
MediHelp also lists interactions of Brompheniramine with, for example, Alfentanil, Belladonna and opium, Benzhydrocodone / acetaminophen. The full list is on the Brompheniramine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
